Generally speaking, lung cancer bone metastasis may hurt at night. Lung cancer bone metastasis refers to when lung cancer enters the advanced stage and the cancer cells are transferred to bones all over the body through blood circulation. Common metastatic sites are spine, pelvis and femur. After lung cancer bone metastasis, the tumor produces damage to the bones of the body, and the pain manifests itself very obviously and is more intense. Due to the excitement of vagus nerve at night, the pain will feel worse than that in the daytime after concentration. In addition, when resting at night, the body is in a quiet state and activities are reduced, which slows down blood flow and aggravates the accumulation of inflammation, which will lead to the aggravation of pain and even unbearable, making it impossible for the patient to fall asleep and causing serious disturbance to life. It is suggested that lung cancer patients should go to specialized hospitals for systematic treatment as prescribed by doctors at an early stage, so as to avoid aggravation of the condition and irreversible damage to the organism.