Adapalene Gel is indicated for the topical treatment of mild to moderate acne vulgaris with acne, papules and pustules as the main manifestation, and can also be used to treat acne on the face, chest and back. The most common side effects of adapalene gel are dry skin, skin irritation, burning sensation and erythema, and possibly contact dermatitis, sunburn, itching, flaking, and swelling of the skin, etc. It may also cause delayed allergic reactions. In case of hypersensitivity reactions or severe irritation, the use of this drug should be temporarily or permanently stopped. If it is accidentally applied to mucous membrane areas, such as the eyes, mouth, nasal mucosa or open wounds, it must be washed with warm water. Care must be taken to protect the skin from the sun when using the medication, and the use of astringent cleansing products, as well as products that can cause dryness or irritation of the skin, such as those with fragrance or containing alcohol, should be avoided at the same time.