Hypotension is a common acute complication during hemodialysis, which generally means that systolic blood pressure falls below 90mmHg and mean arterial pressure falls more than 30mmHg compared with pre-dialysis. The treatment of hypotension in hemodialysis is as follows: 1. Suspend ultrafiltration, nasal catheter oxygen intake, and take the flat position. If conditions, head-down and foot-high position can be used to ensure the blood supply to the myocardium; 2, rapid intravenous input of saline 100mL or more, if still symptomatic, high sugar 20-40mL or 20% mannitol can be given; 3, reset the ultrafiltration rate after the blood pressure improves, and increase the amount of dehydration slowly; 4, if the improvement of hypotension is not obvious after replenishing the blood volume, it is necessary to find out as soon as possible to cause the If the hypotension does not improve after blood volume supplementation, it is necessary to find other causes of hypotension as soon as possible, and can be given antihypertensive medication and stop dialysis, and consider the input of plasma or human albumin.