Uneven endometrial echogenicity is not scary, it may be caused by endometrial proliferative stage, endometrial polyp, endometritis, endometrial cancer, etc. Different causes, different treatments and different healing. 1. Endometrial proliferative stage: this is a normal physiological phenomenon that occurs when the endometrium is affected by estrogen, which usually occurs on the 5th to 14th day of the menstrual cycle. The endometrium gradually proliferates and becomes thicker, and there will be uneven echogenicity in ultrasound examination. 2. Endometrial polyps: when patients suffer from endometrial polyps, ultrasound examination may suggest that the endometrium has uneven echoes. 3. Endometritis: this disease is related to pathogenic microorganisms infection, and the endometrium has inflammatory lesions such as congestion, edema, etc., and the echo of ultrasound is uneven. 4. Endometrial cancer: this disease may be related to estrogen, gene mutation and other factors, cancer cells invade the epithelial cells of the endometrium, resulting in cell detachment, which will lead to uneven echogenicity of the endometrium. There are many factors leading to uneven endometrial echogenicity, which can be treated by timely consultation.