In hydronephrosis, tubular damage may result. Hydronephrosis is the dilatation of renal pelvis and calyces and retention of urine due to urinary tract obstruction, which is often caused by upper urinary tract obstructive diseases, such as stenosis of renal pelvic ureteral junction, stones, etc. Hydronephrosis can lead to renal tubular injury due to the elevated pressure in the kidneys, which presses on the renal cortex and causes glomeruli and tubules in the renal cortex to atrophy and lose their functions. Long-term hydronephrosis will result in obstruction of urination, excessive pressure on the area above the obstruction, and reduced blood flow to the kidneys, which can result in degeneration and necrosis of the renal tubules, and atrophy of the kidneys to become smaller and smaller, resulting in decreased renal function or complete failure of the kidneys, and symptoms such as abdominal mass and distended feeling of the waist are often seen. If symptoms related to hydronephrosis occur, patients are advised to go to the hospital in time, complete the corresponding examination, according to the specific situation, follow the doctor’s advice, and actively cooperate with the treatment.