Glutaric acidemia is a genetic disorder. 1. Glutaric acidemia is an autosomal recessive disorder and is divided into two types. (1) Type I is due to glutaryl coenzyme A dehydrogenase deficiency, which may manifest as headache at birth, vomiting, and neurological symptoms such as hypotonia, uncontrolled head movement, convulsions, and torsion of limbs, and later on, mental retardation. ultrasound may reveal enlarged ventricles of the brain; and brain atrophy can be seen in CT examination. (2) Type II is a fatty acid metabolism disorder, which is due to the deficiency of several acyl coenzyme A dehydrogenases. Severe hypoglycemia, acidosis without ketoacidosis, and hypotonia will occur in the neonatal period. In infancy, cardiac, skeletal, hepatic, cerebral, and renal organ dysfunction may occur. 2. If glutaric acidemia is diagnosed, early and standardized treatment is recommended to reduce the adverse effects of the disease.