It is possible that a small red spot on the glans may be caused by an ordinary bacterial infection, or it may be caused by an unclean sexual contact with syphilis. If syphilis is ruled out and only ordinary bacterial infection is caused, you can choose anti-infection creams such as erythromycin ointment and fusidic acid cream to keep applying to the glans for about two weeks, and the small red spots will slowly disappear. You can also take some oral antibiotics, such as amoxicillin capsules, cefuroxime tablets also have a very good therapeutic effect. If it is clear through the examination that the infection is caused by syphilis, in addition to local glans application cream, you also need to inject long-acting penicillin injection continuous treatment for 2-3 months in order to completely cure syphilis. During the treatment period you should wash the glans secretions with water or iodine volt every day, do not use soap, shower gel and other irritating things, but it will aggravate the symptoms.