The most effective way to treat chronic sinusitis varies according to the cause and condition because of individual differences. Chronic sinusitis is mostly evolved from acute sinusitis, but also related to sinus anatomical factors, allergies, systemic factors, need to choose according to the specific situation can be treated by drug therapy, surgical treatment and other ways of treatment. 1. Drug therapy: glucocorticoid nasal spray, such as budesonide, mometasone furoate nasal spray, etc., to reduce nasal edema, accompanied by allergic rhinitis, antihistamines, such as cetirizine, chlordiazepoxide, etc., to alleviate the symptoms; nasal decongestant, such as furosemide nasal drops and other nasal drops, the course of treatment does not exceed 7 days; mucus drainage agents, such as eucalyptus pinocchio intestinal soft gelatin capsule; nasal irrigation. Treatment. Patients in the acute exacerbation period and patients after nasal endoscopic surgery can also be treated with antibiotic drugs, such as amoxicillin clavulanate potassium, roxithromycin, clarithromycin and so on. 2. Surgical treatment: If the sinuses have obvious structural abnormalities; polyps affecting the nasal sinus complex or sinus drainage; more than 12 weeks of standardized drug therapy, unsatisfactory improvement of symptoms; the occurrence of intracranial and intraorbital complications, nasal endoscopic surgical treatment, general endoscopic sinus open surgical treatment. Chronic sinusitis patients after standardized treatment, the prognosis is better, it is recommended that patients seek medical treatment in a timely manner, in accordance with the doctor’s instructions for treatment.