Cranial defect is a common disorder nowadays, and there are many reasons that can lead to cranial defect in normal life, such as fights, traffic accidents and craniotomy, which may leave cranial defect behind. Skull defect is not just a small problem, it is not only related to the aesthetic image, but also has a great impact on safety. Because after skull defect, the brain is unprotected and the safety is greatly reduced, and if the intracranial tissues are accidentally damaged by the outside world, the situation will be even worse. Moreover, cranial defect will cause the intracranial pressure and intracranial environment to become unstable, and the cerebrospinal fluid circulation and blood circulation will be affected, resulting in a series of physical discomfort symptoms. Strictly speaking, as long as the skull defect is more than 3 cm in diameter, it should be actively treated and repaired, and skull repair surgery is not a big operation in neurosurgery, it is very safe and can be done in general hospitals. As for the general cost of skull repair surgery, this cannot be generalized, because each patient’s situation is different, the surgical plan taken and the repair materials chosen are different, all of which will affect the specific cost of treatment. Especially the choice of skull repair materials, which not only affects the price, but also has a great impact on the results of the surgery.