If lung cancer in advanced stage causes dyspnea, it is necessary to carefully identify what causes it. If lung cancer in advanced stage leads to systemic failure, severely reduced cardiopulmonary function, hypoproteinemia, which is cachexia, patients with dyspnea need to be given enhanced nutritional therapy, including intravenous infusion of human albumin and various oral nutritional solutions to improve protein level and dyspnea. If lung cancer belongs to central type lung cancer with obstructive pneumonia, which causes serious lung infection or even blood in the sputum, patients with respiratory distress need to actively seek solutions to relieve lung cancer, including surgery, chemotherapy, radiotherapy and other means. If lung cancer is accompanied by large amount of pleural effusion causing dyspnea, chest aspiration as well as continuous closed chest drainage should be given as soon as possible to drain the effusion to improve the symptoms of dyspnea. The dyspnea in late stage of lung cancer is also seen in the complications of lung cancer, including asthma, hypertension, myocardial ischemia and other symptoms caused by concomitant cancer syndrome.