Infertility is defined as a diagnosis of infertility when a couple has been living together and having normal sex for more than one year without contraception. There are many causes of infertility. When there is a history of infertility for more than 1 year, the couple should go to the male and female departments of the fertility center for separate examinations. In the case of the male partner, the routine semen, physical examination, sexual function tests, sperm DNA fragmentation, and the presence of hepatitis B, syphilis, and AIDS are usually checked. In addition to the normal physical examination and routine blood biochemistry tests mentioned above, the woman also needs to check some special items, such as tubal imaging to check whether the fallopian tubes are open, whether there is any obstacle to ovulation, and whether the uterine cavity is combined with organic lesions, such as endometrial polyps, leiomyosarcoma, and other factors affecting the implantation of the embryo. When the couple find out the cause of the disease, and then to solve the cause, targeted treatment, through the infertility of the cause of the cure and then again to help conceive, if still can not conceive naturally, can also be through assisted reproduction technology, such as artificial insemination or in vitro fertilization to help conceive again.