Squamous carcinoma cell-associated antigen is an important marker for squamous epithelial carcinoma, and its elevation is mainly seen in squamous cell carcinomas such as cervical carcinoma, lung squamous carcinoma, and head and neck squamous carcinoma. Squamous cell-associated antigen is found in the cytoplasm of squamous cell carcinomas, and the degree of elevation is closely related to the degree of malignancy of the tumor. However, in some benign diseases, squamous carcinoma-associated antigen is also elevated to a certain extent, such as tuberculosis, hepatitis, cirrhosis of the liver and so on. Squamous carcinoma-associated antigen is often used in treatment monitoring and prognosis judgment, such as judging the therapeutic effect of anticancer, and when the tumor recurs or progresses, squamous carcinoma-associated antigen can be elevated again. Patients should consult doctors in time and complete relevant examinations under the guidance of doctors in order to make a clear diagnosis and improve the prognosis with timely treatment.