As a kind of orthopedic clinical medical material, bone cement is widely used in joint replacement and other surgeries, the general use of the effective period is 2~4 years, but if it has been injected into the bone, except for the loosening of the bone cement to fall off, it is generally not necessary to remove. The service life of bone cement often depends on many factors such as the surgery done by the patient, the material chosen, and the disease environment after the surgery. 1. Diseases of patients: if it is lumbar compression fracture, using minimally invasive surgery of bone cement cone molding, the bone cement can exist for a long time; if it is joint replacement with bone cement, its service life is generally 15~20 years. 2. The material used: Bone cement can be categorized into PMMA type and CPC type, meanwhile, the products produced by different manufacturers are also slightly different, PMMA type bone cement has a longer lifespan due to its biological inertness; if it is CPC type bone cement, it has a certain degree of biodegradability, and its lifespan is relatively limited. 3. Postoperative disease environment: if the patient’s injury site is repeatedly movement, then it is difficult to avoid loosening of the bone cement, or infection, at this time, the bone cement should be taken out and replaced in 3~4 weeks. In conclusion, the service life of bone cement depends on many factors, the use of different diseases with different methods and purposes, the length of its use is also different.