The differentiation between benign and malignant ascites includes the rate of ascites production, nature of ascites, ascites detection, and primary disease. 1. Ascites generation rate: benign ascites usually generates slowly; while malignant ascites generates faster. 2. The nature of ascites: benign ascites is usually clear or turbid; malignant ascites is usually washed or bloody. 3. Ascites test: In ascites test, if the ratio of tumor marker CEA in ascites to CEA in serum is more than 1, or the lactate dehydrogenase content in ascites is more than 500U/L, or detached cancer cells can be found in ascites, then it is mostly considered to be malignant ascites; otherwise, it is mostly considered to be benign ascites. 4. Primary disease: if there is malignant tumor primary foci, such as liver cancer, pancreatic cancer, etc., then it is mostly considered as malignant ascites; if the primary disease is cirrhosis, hypoproteinemia, heart failure, etc., then it is mostly considered as benign ascites. The above are some of the differences between benign and malignant ascites, and it is recommended to consult a doctor in time for diagnosis by a professional doctor.