Normal prostate anterior-posterior diameter of about 2cm, if the prostate anterior-posterior diameter of 45mm is serious. Clinical examination found that the normal male prostate transverse diameter of about 4cm, vertical diameter of about 3cm, anterior and posterior diameter of about 2cm. therefore, the prostate anterior and posterior diameter of 45mm more than the normal size, need to be vigilant is prostatitis, prostate hyperplasia, prostate cancer and other diseases caused by prostate enlargement, is usually serious, and should be taken seriously. In addition to the abnormal anterior and posterior diameters of the prostate, it is also easy to be accompanied by an increase in local secretions, urinary frequency, urinary urgency, urinary pain and other symptoms, which have an impact on the quality of life and health. If the patient does not pay attention to it and the condition further aggravates, it is easy to increase the difficulty of treatment, reduce the prognosis, and even endanger the life. It is recommended that people with prostate diameter of 45mm should undergo further detailed examination, such as CT and prostate MRI, in order to clarify the cause of the disease and follow the doctor’s instructions for treatment, and to promote the recovery of the body’s health. Pay attention to personal hygiene care, try to wear cotton, loose underwear, and avoid unclean sex.