Feet peeling long blisters (i.e. “blisters”) and itchy, may be tinea pedis, sweat herpes, eczema and other diseases, should be based on the cause of the disease, through the general treatment, medication and other methods of treatment. 1. Tinea pedis: it occurs in the toe area or soles of the feet, and the typical symptoms are skin erythema, dandruff, blisters, erosion and so on. Patients should pay attention to keep the feet breathable, at the same time, external use of tretinoin econazole cream and other glucocorticoid drugs, if necessary, follow the doctor’s instructions oral itraconazole capsules, terbinafine tablets and other antifungal drugs. 2. Sweat herpes: blisters may appear on the hands or feet, accompanied by obvious itching. Often use glycerite lotion to astringent anti-itching effect, can also be used externally tretinoin urea cream and other glucocorticoid drugs, but also oral antihistamine drugs such as loratadine as prescribed by the doctor. 3. Eczema: the patient’s feet will appear small blisters, itching is very serious, there will be liquid oozing after breaking the skin. When the blisters are broken and oozing, boric acid solution can be used externally as a wet compress, and when the blisters are dry and not oozing, glucocorticosteroid ointment such as mometasone acetate cream can be used externally, and antihistamines such as cetirizine hydrochloride tablets need to be taken orally. It is recommended that the patient actively seek medical attention, after a clear diagnosis, strictly comply with the doctor’s instructions to use medication to alleviate the symptoms.