Whether neonatal jaundice index reaches 17~18mg/dL is serious or not is related to the specific conditions of neonatal age, weight, and their own conditions, which are pathological jaundice, and it is recommended to consult a doctor as early as possible for treatment. Neonatal jaundice index should not be more than 15mg/dL, when the neonate is born at full term, with normal body weight of more than 2.5kg, and the jaundice index reaches 17~18mg/dL after three days of birth, which is generally not serious, the jaundice index of the neonate reaches the peak at this time, and the neonate should be treated according to the doctor’s instruction. The jaundice index reaches 17mg/dL within 24 hours after birth, or the newborn is born prematurely, with abnormal weight, belonging to very low birth weight and ultra-low birth weight, and the jaundice index reaches 17mg/dL, which is more serious. At this time, the jaundice index of newborns rises rapidly, usually hyperbilirubinemia, if not treated in time may cause bilirubin encephalopathy. There are many causes of pathologic jaundice, but whatever the cause, when jaundice reaches its peak, it should be treated promptly to avoid aggravation of the disease. If infants with hyperbilirubinemia can be treated in time, the result will be very good, which can effectively reduce the risk of affecting growth and development and sequelae. When you find that the index of jaundice is high in newborns, you must go to the hospital in time, so as not to miss the optimal time for treatment.