If the nodule appears again after liver surgery, if it is a benign lesion, regular review is enough, if it is a recurrence of hepatocellular carcinoma, then it needs to be controlled by surgical treatment, interventional therapy, targeted therapy, immunotherapy and other methods. If the nodule appears again after liver surgery, if the nodule is benign, grows slowly and has no blood flow signal, regular checkups are enough, but if it is too big and causes symptoms, partial hepatectomy can be used for treatment. If liver cancer exists in the past, the reappearance of nodules at this time may be a recurrence of liver cancer, and comprehensive treatment is needed. Partial hepatectomy or radiofrequency ablation surgery, or interventional therapy combined with targeted therapy (e.g. sorafenib, lenvatinib, etc.) can be chosen to promote the shrinkage of nodules and prevent them from continuing to develop. After liver surgery, it is necessary to pay attention to regular review, and if the nodules are found again, it is necessary to consult a doctor in time, and carry out standardized treatment under the guidance of the doctor to promote the remission of the disease.