Diffuse large B-cell lymphoma must be treated with chemotherapy. It is a type of lymphoma that is sensitive to chemotherapy drugs, and chemotherapy drugs can cure diffuse large B-cell lymphoma disease in its early stages. Therefore, chemotherapy is the most important form of treatment for diffuse large B-cell lymphoma. For example, some patients with a mass in their neck about the size of an egg completely disappeared after 4 cycles of the R-CHOP regimen, which proves how effective chemotherapy is for diffuse large B-cell lymphoma.