Taking glibenclamide may cause hypoglycemia, diarrhea, nausea, vomiting, headache, stomach pain and other uncomfortable symptoms, it is recommended to take the drug under the guidance of a doctor. Glibenclamide is a sulfonylurea hypoglycemic drug for type 2 diabetes mellitus, which exerts a hypoglycemic effect by promoting insulin secretion. Inappropriate use of glibenclamide may cause hypoglycemia, resulting in symptoms such as panic, dizziness, profuse sweating and tremor. In addition, taking glibenclamide may cause adverse reactions such as diarrhea, nausea, vomiting, headache, stomach pain, rash, and in serious cases, jaundice, liver function impairment, bone marrow suppression, granulocytopenia (manifested by sore throat, fever, infection), thrombocytopenia (manifested by bleeding, purpura) and other adverse reactions. It is recommended to follow the doctor’s instructions to standardize the use of drugs, do not blindly self-use. If discomfort occurs, please consult a doctor promptly.