High-grade precancerous lesions of the cervix are often treated by conization. If the margins of the conical resection have been cleanly cut, it will often turn negative, and it is recommended that a follow-up examination be given at 3 months, 6 months, and 1 year after the operation. Even if the test is negative, the patient may still be infected with high-risk HPV, which may lead to pre-cancerous changes in the cervix, so regular check-ups are especially important. It is recommended that the patient should undergo regular check-ups, and if abnormalities are detected, the patient should be treated as soon as possible to prevent the occurrence of cervical cancer. Therefore, after conization surgery, most people will become negative, but regular review is especially important, if abnormalities are found, the clinic will actively give treatment.