Ibuprofen is usually taken at intervals of 4-6 hours, but must not be taken more than four times within 24 hours. When ibuprofen is used to reduce fever, if the symptoms are not relieved after three days, it is recommended to stop the drug and seek medical advice. If it is used for pain relief and the symptoms are not relieved after five days, it is also recommended to stop taking it and seek medical advice. Do not take other antipyretic and analgesic drugs, such as naproxen, indomethacin, acetaminophen, etc., while taking ibuprofen, because taking these drugs together is likely to increase the irritation of the gastrointestinal tract, and also increase the damage to the liver and kidneys, which will increase the adverse effects of the drug.