The full name of tsh receptor antibody is thyrotropin receptor antibody (TRAb), which is an indicator for diagnosing Graves’ disease. Whether or not TRAb 2.5 is serious mainly depends on the function of the thyroid gland, if the function of the thyroid gland is elevated, it will be relatively serious; if the function of the thyroid gland is completely normal, it will not be serious. Positive thyrotropin receptor antibody and thyroid function suggesting hyperthyroidism are relatively serious conditions, and are considered to be Graves’ disease, which needs to be controlled with regular anti-thyroid medication. If the thyroid function is completely normal, it is not very serious and regular review is recommended. TRAb2.5 should be treated under doctor’s supervision.