Urinalysis with leukocyte esterase ± and other normal is usually divided into two cases. The first is seen in strenuous exercise or fever, etc.; the second may suggest urinary tract infection, etc. 1. Leukocyte esterase is mainly found in neutrophils and histiocytes, and its content is very low in lymphocytes and monocytes. Urinary leukocyte esterase± may occur during strenuous exercise or fever, otherwise it is normal and may return to normal after rest or fever subsides. 2. Urine leukocyte esterase ±, other normal may suggest that the urinary system has purulent inflammation such as pyelonephritis, cystitis, urethritis, etc., at this time, should improve the urinary nitrate test, urine pH and other tests, according to the urine culture and drug sensitivity results of the selection of appropriate antibiotic treatment. Urine test white blood cell enzyme appears ± situation, it is recommended to go to the hospital, under the guidance of specialists to improve the relevant examination, to clarify the cause, timely treatment.