Syphilis vulva may be characterized by erythema, papules, ulcers, pustules, itching, and mucous discharge. It may also be asymptomatic in the early stages of general infection. Syphilis is a chronic, systemic sexually transmitted disease. Typically, syphilis patients will develop a hard chancre on the vulva, which may be characterized by the presence of a localized round or oval red spot or papule with clear borders and a hard texture. As the disease progresses, the localized erythema may become necrotic and then form a painless ulcer, which may have a small amount of mucous discharge. Secondly, some patients will have pustules at the vulvar mucosa, accompanied by mild itching. In the case of men, they often occur on the penis, glans, prepuce and tether, and in the case of women, they often occur on the labia, perineum and uterine opening. If you are diagnosed with syphilis, you should actively follow the doctor’s instructions for treatment so as not to delay your condition.