Tracheal stenosis and tracheal tumors are usually initially diagnosed by bronchoscopy. In simpler cases, they are also treated via tracheoscopy. They can be clamped, electrocautery, frozen, laser. In some cases, a cure can be achieved. In some complex and large tracheal involvement cases, endoscopic treatment is less effective, difficult to achieve a cure, and sometimes even difficult to relieve symptoms. In this case, surgical treatment is required. In comparison, among the several methods of endoscopic treatment, cryotherapy is desirable. Because of the danger of cryotherapy, the effectiveness is relatively better. Electrocautery laser are thermal effects, the damage is large, and even cause perforation of the tube wall. If there is medical combustible gas, even burns occur. Freezing leaves a very light scar, freezing can also reduce bleeding, more conducive to further treatment operations. Frozen tissue of the ring dead, but also can become a stimulation of the body’s immune antigen, secondary to the body’s immune response, thus playing a certain inhibitory effect on tumors and other diseases. In conclusion, cryopreservation is a widely used intracavitary therapy. I was the vice president of the International Society for Cryosurgery, so I have a special respect for cryosurgery. Cryotherapy has a history of several thousand years, but it is not well developed because of technical bottlenecks. The cryoprobe cannot be solved. The freezing probe in the eighties was still very thick and clumsy, more than 1 cm in diameter, the pipe was a metal thick snake skin tube, the freezer was like a vertical air conditioner like the size of the clinical application is not only poor, and very inconvenient. In fact, throughout the eighties, domestic cryonics was in a stagnant state. In the early 1990s, I studied at Harefield Hospital in London and was fortunate enough to receive a lecture from Professor Maiwand, President of the International Society of Cryosurgery. He focused on getting me to master cryosurgery for lung cancer at that time, mainly using metal rigid bronchoscopy. When my lung transplant study was completed, he gave me a British-made cryotherapy machine before I returned home. It was not much bigger than a video. More importantly, I was given a cryo-probe free of charge. And the probe was his personal patent. He predicted that you could quickly copy the cryo machine, but the probe would take ten years. He underestimated the pace of China’s reform and opening up. After returning to China, I used the machine to complete animal experiments and clinical research on “freezing intercostal nerves for the prevention and treatment of pain in open-heart surgery”. Four papers were published in national medical journals and foreign medical journals. At this time, Mr. Guo Yuanzhao, a dedicated member of the society, discovered its business opportunities and established a freezing equipment development company, later called Cooland. With the prototype I brought back, we built a cryotherapy machine that could be used clinically in China. It was beautiful in appearance and light in movement. Soon after, many thoracic surgeries across the country carried out this technology, which greatly reduced the pain of patients after open-heart surgery. But after all, cryotherapy was only carried out in the field of thoracic surgery. Later, at my suggestion, the manufacturer developed a fiberoptic catheter that could introduce cold air, and at once, endotracheobronchial cryotherapy via fiberoptic bronchoscopy was widely carried out. In 2000, I invented the world-leading “bronchial blockage method for pulmonary decongestion of emphysema”, which was published in the Journal of China-Japan Friendship Hospital and then in the Chinese Journal of Thoracic and Cardiovascular Surgery in 2001, and was the first case in the world to introduce and apply this method. In the years since then, this method has become popular worldwide. It has also gained considerable scale in China. Bronchoscopic endoluminal treatment, including cryotherapy, is becoming more and more widely used in clinical practice. The photo below shows a tumor in the trachea with a largely obstructed lumen. The lower left photo shows the local scar left after cryotherapy, and the lumen of the trachea has been completely opened up. Cryotherapy is performed by inserting a fiberoptic probe into the swelling or stenosis through the biopsy hole of the fiberoptic bronchoscope, then turning on the treatment machine, turning on the refrigerant, freezing the lesion, hardening it, and removing the necrotic material with biopsy forceps. There is usually little or no bleeding. It should be said that cryotherapy is not a panacea and can only deal with smaller tumors. The stenosis is relatively mild and the lesion is relatively small in extent. But after all, in most patients with tracheal stenosis and tumors, the first treatment can be considered cryotherapy. If the result is not good, early surgical resection treatment is recommended. Here I would also like to recommend Dr. Wang Hongwu of Beijing Coal General Hospital, who has done a lot of clinical practice in this area for many years and has accumulated too much experience, saving the lives of a large number of critically ill patients. Patients can go to him for medical treatment. If you need surgery, welcome to my place!