The stimulation of the gastrointestinal tract when aspirin and clopidogrel tablets are taken at the same time is certainly great, the milder ones can lead to superficial gastritis, the more serious ones can lead to gastrointestinal bleeding and even the appearance of peptic ulcers, therefore, nowadays most of the clinical use of aspirin enteric tablets to reduce the stimulation of the stomach, in the past when aspirin and clopidogrel tablets were taken orally it was recommended to take them on an empty stomach, now more and more doctors for patients with previous gastric diseases It is recommended to continue taking them after meals, which is to reduce their irritation to the class of drugs. Meanwhile, both aspirin and clopidogrel tablets are anti-platelet aggregation, so its biggest side effect is bleeding. Clinically for senior patients is often seen to have gastrointestinal tract out, blood brain bleeding, so be sure to clearly take two oral antiplatelet drugs as prescribed by the doctor, while it is recommended to take after meals, and the two drugs try to avoid taking at the same time, you can use the morning or noon respectively, in order to reduce the risk of irritation of the gastrointestinal tract and bleeding caused by taking both at the same time.