High serum β2 microglobulin is usually the result of reduced glomerular filtration rate and damaged renal tubules. Serum β2 microglobulin appears in the five items of premature renal loss, which is a specific indicator of early functional impairment of glomeruli and tubules. When the serum β2 microglobulin is high, it is necessary to achieve a low protein diet, especially to limit the intake of vegetable protein, and animal protein should be reduced as much as possible, but a certain amount of refined protein should be supplemented, and the refined meat of fish, shrimp, crab and the refined meat part of beef and mutton can be supplemented appropriately, but the intake of soy products should be avoided as much as possible. You can also take certain Chinese medicines, such as Cordyceps sinensis, Jin Shui Bao, Huang Quai capsule, all can play a role in reducing the effect of serum β2 microglobulin, do not take certain or excessive amount of drugs that hurt the kidneys and drugs that increase the metabolism of the kidneys.