Analgesics, also known as painkillers, refer to medications that partially or completely relieve pain. Clinically used painkillers are usually divided into five types: non-steroidal anti-inflammatory drugs, central painkillers, narcotic painkillers, antispasmodic analgesics, anxiolytic painkillers. 1. Non-steroidal anti-inflammatory drugs: pain effect is not strong, but there is no addiction, the use of more widely and safely, the efficacy of clear. Commonly used in fever and cold and other common pain. Including commonly used aspirin, ibuprofen and so on. 2. Central painkillers: stronger than general painkillers, mainly used for a variety of moderate acute pain and post-surgical pain. Including Tramadol, etc. 3. Narcotic painkillers: strong analgesic effect, but there is addiction, so the state management of these drugs is strict, mainly used in cancer patients with severe pain, the representative drugs are morphine and so on. 4. Antispasmodic and analgesic drugs: general analgesic effect, commonly used in the gastrointestinal tract and other smooth muscle spasmodic pain. Representative drugs are atropine, scopolamine and so on. 5. Anxiolytic analgesics: general analgesic effect, commonly used in patients suffering from anxiety, insomnia and other symptoms of headache, the drug can make the patient’s emotional stability, muscle relaxation. The representative drugs are diazepam, paroxetine and so on. Daily life in the use of drugs must need to pay attention to, to know to distinguish between the common types of painkillers, after listening to the guidance of professionals to rationalize the use of painkillers, to reduce unnecessary damage.