The cause of headache and insomnia may be due to mental psychological factors, neurasthenia, hypertension and other causes. In terms of treatment, the main thing is to regulate the mood, the application of relevant therapeutic drugs for the original disease. 1. mental psychological factors: if it is due to the recent psychological stress, emotional over-anxiety caused by headache and insomnia, the main thing is to do a good job of adjusting their own state of mind, so that the inner pressure can be released to maintain a relaxed mood, which is conducive to improving the headache and insomnia. 2. Neurasthenia: If it is due to neurasthenia caused by long-term sleep disorders, resulting in headaches and insomnia, can be directed by the doctor to apply antidepressant, anti-anxiety drugs, such as sertraline, paroxetine, etc., is conducive to make the patient’s depression, anxiety can be improved, and then alleviate the headaches and insomnia. 3. Hypertension: If the headache and insomnia are caused by increased pressure inside the cerebrovascular system due to elevated blood pressure, after a clear diagnosis, the main application of antihypertensive medication is to alleviate the problem, and commonly used medications are nifedipine, irbesartan, and so on. Headaches and insomnia should be timely medical attention to find triggers, for the triggers of targeted treatment and conditioning.