Running foot abrasion blisters, it is recommended to reduce exercise, pay attention to the care of the affected area. Give topical medication to apply, if necessary, go to the hospital to ask the doctor for treatment. 1. Pay attention to care: too much running may cause local irritation, resulting in blisters on the soles of the feet. It is recommended to reduce walking to avoid localized irritation. Wear loose, cotton, breathable shoes and socks to avoid friction. 2. Topical medication: if the blisters are relatively small, such as the size of a grain of rice, you can use glycerine lotion, mometasone furoate cream, hydrocortisone butyrate cream and other topical application, which can promote the disappearance of the blisters. 3. Go to the hospital for treatment: if the blisters are large, such as the size of grapes, it is recommended to go to the hospital outpatient clinic and ask the doctor for treatment. If you use a sterile needle to extract the liquid in the blisters, together with the comfrey oil morning and evening external application, can promote the recovery. It is recommended to wear suitable shoes when running to avoid friction on the foot. Localized blisters, if necessary, go to the hospital, the above drugs need to be used in accordance with medical advice.