Benign familial neonatal convulsions are a rare autosomal dominant neonatal partial epilepsy syndrome. The cause is related to a mutation in the potassium channel, and 80% of children have their seizures on the second to third day of life, commonly referred to as “three-day wind”. The seizures begin with generalized tonicity, followed by various autonomic symptoms (apnea, cyanosis, heart rate changes, etc.), motor symptoms (bilateral or partial clonus, which may wander from one side to the other), and automatic symptoms (sucking, chewing, etc.). There are no myoclonic and spastic seizures. A seizure usually lasts 1 to 3 minutes, and there are often recurrent seizures within 1 week, and later there can be a small number of single seizures with a tendency of self-healing and a good long-term prognosis. The interictal EEG is normal or mildly delayed in maturation, with focal or multifocal spike waves, or alternating spike-shaped theta waves, mostly in quiet sleep, often asynchronous in both hemispheres. No graphics suggestive of poor prognosis such as hypovoltage, electrical suppression, reactive deficit or burst-inhibition were seen. The seizure EEG initially shows widespread suppression of background activity for 5-20 seconds, followed by localized spike and spike wave rhythmic discharges of various frequencies and waveforms, or single rhythmic discharges in the δ, θ, and α bands, most often in the Rolandic area. As the seizure progresses, the localized discharges may spread or wander to other areas or even to the contralateral hemisphere. A complete seizure lasts anywhere from 60 to 150 seconds. Sometimes there are only electrical seizures.