The fever of HFMD usually subsides in about 3-5 days. HFMD is a contagious disease caused by enterovirus infection. Infants and children under 3 years old are susceptible to the disease, which is mainly transmitted through the intestinal tract, respiratory tract, and close contact. Although ordinary cases may be febrile, the body temperature usually does not exceed 38.5°C. Patients with mild HFMD have a relatively short onset and recover relatively quickly, and are generally cured basically in about 1 week, and patients usually have a fever for no more than 5 days. However, if the fever lasts for more than 5 days, or if the fever stays high, it is important to consider whether the HFMD is severe, and it is recommended to visit the infection department in time to cooperate with the doctor’s treatment. Patients with HFMD fever can follow medical advice to assist antipyretic medication to prevent discomfort caused by high fever, and can also take physical cooling methods, such as wiping the body with warm water, which can promote heat dissipation and achieve cooling effect.