A macula on the white eyeball cannot usually be made to go away by medication and can be removed by surgical treatment. Yellow spots on the white eyeballs are usually caused by conjunctival nevus, scleral nevus and blepharospasm. Conjunctival nevus pigmentosus and scleral nevus pigmentosus are usually formed due to congenital developmental abnormality, resulting in deposition of pigment particles in the local tissues, which generally do not endanger eye health or cause discomfort, but only have some effect on appearance. Blepharospasm is caused by aging phenomenon which leads to degeneration and proliferation of local conjunctival tissues, which will protrude on the surface of the eyeball and may cause symptoms such as foreign body sensation in the eye. For treatment, these lesions can be surgically removed to improve their appearance. If the patient does not feel that the above lesion has a significant impact on his/her appearance and does not experience discomfort, then the patient can leave it untreated for the time being, but should keep an eye on the lesion to see if it develops. If you find a yellow spot on the white eyeball, you should go to the ophthalmology department of the hospital and be diagnosed by the doctor to determine whether treatment is needed.