In terms of anesthesia alone, a single general anesthesia is usually not harmful to the brain, but a certain amount of physical discomfort, such as dizziness and nausea, may occur after the operation, and the corresponding reactions may disappear after the effects of the anesthetic drugs have worn off. If it is a brain disease or surgery, the influencing factor is usually these two, rather than the factor of carrying out one general anesthesia. General anesthesia methods include inhalation anesthesia, intravenous anesthesia and static-absorption combined anesthesia, regardless of the way, the blood concentration of anesthetic drugs in the center can be regulated. After a general anesthesia operation, after the dissipation of the effect of anesthetic drugs, the patient’s consciousness and various reflexes can be restored, so generally will not have an impact on the brain. After general anesthesia, the patient’s various systems and organs are usually in a relatively normal state, allowing the completion of the operation, usually no need to worry. Before general anesthesia will be a comprehensive assessment, the patient should be detailed and honest to the anesthesiologist to indicate their own situation. If the patient intentionally conceal their condition, resulting in anesthesia drug allergy, heavy shock can cause brain damage, and the extent of the damage is usually incalculable, the timely rescue may be less severe, and some may be very serious and life-threatening.