When a blood blister breaks on the tongue, an ulcerated surface will appear on the tongue, and the treatment mainly consists of reducing irritating factors, local use of anti-inflammatory, analgesic, and healing-promoting drugs, such as 0.1% tretinoin ointment, chlorhexidine gargle solution, lidocaine gel, and recombinant human epidermal growth factor gel. 1. Reduce the stimulating factors: should eat less acid, spicy, hot and other stimulating food, adjust the grinding too sharp tooth tip, remove dental calculus, remove bad restorations, keep the oral cavity clean. 2. Local anti-inflammatory, analgesic, healing drugs can be used, such as anti-inflammatory 0.1% tretinoin ointment, chlorhexidine gargle, etc., analgesic, such as lidocaine gel, spray. Drugs to promote healing, such as recombinant human epidermal growth factor gel. If long-term non-healing, it is recommended that the hospital timely consultation, the use of drugs need to follow the doctor’s advice.