SMA generally refers to spinal muscular atrophy, which is an autosomal recessive disease. The cause of the disease is still unclear. Patients often suffer from muscle weakness, tremor and other symptoms, and need to follow the doctor’s prescription of medication or surgical treatment. The cause of spinal muscular atrophy is still unclear, but the disease is mainly due to genetic mutations. Common symptoms include generalized weakness, dysphagia, dyspnea, poor motor development, scoliosis, frequent falls, etc. It is also easily accompanied by coughing weakness, constipation, hand tremor, etc., which has a serious impact on the quality of life and health. For spinal muscular atrophy, respiratory assistance is usually required, and nasoenteric tube feeding is recommended for those with swallowing difficulties. Commonly used therapeutic drugs include nociceptin sodium injection, which can increase the production of neuromotor survival gene proteins, thus improving the discomfort. For those with concomitant scoliosis, surgical correction is possible. It is recommended that people with spinal muscular atrophy actively cooperate with their doctors in order to improve their discomfort and quality of life. In daily life, patients can do limb flexion and extension activities, balloon blowing exercises, etc. Appropriate exercise is also beneficial to the improvement of the condition, but overwork should be avoided.