First look at the normal range of this test, if it is still within the normal range, it is not serious, but it is time to be alert. If it has exceeded the upper limit of normal, creatinine 124umol/L is still more serious at this time. Because creatinine belongs to the metabolic waste of human body, which is mainly metabolized and excreted by kidneys, after high creatinine often indicates more than 50% decrease of kidney function. In this case, you should first go to the nephrology department of the hospital to check urine routine, urine protein quantification and kidney ultrasound. Based on these indicators, we can determine whether there is glomerular disease, such as glomerulonephritis or other diseases that cause kidney damage. If the kidney morphology and function are basically normal, the creatinine elevation may be early, when the progression of kidney function to the uremic stage can be stopped by active drug intervention to slow down the deterioration of kidney function. If there is reduced kidney morphology or structural disorder and unclear corticomedullary junction, this condition suggests elevated creatinine caused by chronic kidney disease, and the more common cause is chronic nephritis, which will eventually develop into the uremic phase if not intervened.