Kawasaki disease, i.e. cutaneous mucocutaneous lymph node syndrome, there are two kinds of aspirin dosage reduction programs in the treatment process, one is to gradually reduce the dosage after 3~5 days of fever reduction, and the other is to directly reduce the dosage.
1. Gradual reduction: after 3~5 days of fever, from the initial measurement of 30~50mg/Kg per day, gradually reduce the dosage, each time by 2mg, within two weeks to 1 day 3~5mg/Kg, and maintain this dose for 6~8 weeks.
2. Direct reduction: after 3~5 days of fever reduction, reduce aspirin to 3~5mg/Kg per day and maintain this dose for 6~8 weeks.
When the child is combined with coronary artery disease, aspirin needs to be maintained at 3~5mg/Kg daily until the coronary artery returns to normal.
Common adverse effects of aspirin are gastrointestinal ulcers, bleeding, long-term high-dose medication needs to be gastric protection, and avoid combining with other non-steroidal drugs, such as ibuprofen, acetaminophen, etc., and serotonin disease patients should be careful to use aspirin, the adjustment of the dose of the therapeutic process needs to be adjusted by the doctor according to the assessment of the disease, do not adjust the medication by yourself.