Some of them are normal and may be pathological during in vitro fertilization, which may include the following: a. Because the ovaries are enlarged after the use of ovulatory drugs, they may compress or pull the local tissues to cause discomfort, which can be caused without special treatment and rest. Second, it may also be caused by ovarian hyperstimulation syndrome due to improper use of ovulatory drugs, which can cause ascites, belly distension, and generalized swelling. If there is abdominal distension, you need to go to the hospital for ultrasound examination, if there is ascites consider ovarian stimulation syndrome, under the guidance of the doctor reasonable medication to regulate, pay attention to rest, do not exercise strenuously. If the ovaries are overstimulated, it is easy to cause ovarian rupture and pain. If the ovaries are ruptured, timely surgery is needed to avoid adverse consequences, and it is best to review the ultrasound regularly after ovulation and pay attention not to stay up late.