Itchy grooves on both sides of the female urethra may be the cause of urethritis, urethral stomatitis, vulvovaginitis, and should be promptly consulted to identify the cause of the disease. 1. Urethritis: When women have unclean sex or do not pay attention to hygiene, gonococcus, mycoplasma and other pathogenic bacteria infection can occur, which in turn induces urethritis. If stimulated by inflammation, it may lead to itchy grooves on both sides of the urethra, and may also be accompanied by symptoms such as frequent urination, urinary urgency and painful urination. In addition, the inflammation that occurs in the area of the external urethral opening may be the external manifestation of urethritis, which is mostly a non-specific bacterial infection, and may also be caused by pathogens such as diplococcus gonorrhea and trichomonas. Local inflammatory infections can make the female urethra itchy on both sides of the groove and other symptoms. 2. Vulvovaginitis: If there is urine stimulation, local moisture and other factors, it is easy to induce vulvovaginitis, which may lead to female urethral grooves itching, may also be accompanied by tingling, erythema and other symptoms. If found that the urethral grooves on both sides of the itch, the patient should pay attention to not scratching, should keep the local dry, hygiene, and diligent change of underwear, do not wear tight-fitting underwear, and timely to the regular hospital for diagnosis and treatment.