I believe that many patients have had the experience of being diagnosed with “chronic pharyngitis” or “chronic laryngitis” after visiting the otolaryngology department for symptoms such as dryness, pain, hoarseness, foreign body sensation, burning sensation and chronic cough. Patients often go through a variety of tests describing congestion and even swelling of the pharyngeal mucosa, lymphatic follicle hyperplasia and other manifestations, for which they take a large number of so-called pharyngitis drugs, anti-inflammatory drugs, etc., and even undergo laser and so-called plasma surgery for this purpose without obtaining substantial results, and some even have different degrees of psychological disorders as a result. You may not believe it, but in fact about 80% of these patients are suffering from “reflux laryngitis”. Some people may ask how can I be diagnosed with reflux pharyngitis when I don’t have obvious symptoms of burning pain in the throat, acid reflux, heartburn, stomach pain, bloating and other digestive tract symptoms, but this is also a cause of misdiagnosis, because some patients with reflux disease do not have obvious reflux symptoms, or there are no reflux symptoms during the day and reflux only occurs at night during sleep, which is called invisible reflux. Some patients do not even observe reflux during gastroscopy. If the doctor does not have the knowledge or does not take a careful history to follow up on the signs of reflux, misdiagnosis and mistreatment are inevitable. So how does reflux disease occur? We know that under normal circumstances, when food enters the cardia, the entrance to the stomach, through the esophagus, the cardia sphincter closes and the stomach contents, such as food and stomach acid, cannot reflux into the esophagus or higher. When the lower part of the esophagus and the cardia sphincter is relaxed for various reasons, the role of this one-way valve is weakened or disappeared resulting in the reflux of gastric contents into the esophagus and even the throat, stimulating the local mucosa, causing the above-mentioned throat discomfort symptoms, if combined with gastric dysfunction and other conditions or lying down after meals, the chance of acid reflux into the throat increases significantly, and the symptoms are more obvious. Therefore, for those patients with chronic pharyngitis that is untreated and repeatedly prolonged, in addition to consulting with respiratory medicine and cardiovascular medicine to exclude allergic hyperreactive diseases of the airway such as asthma and myocardial ischemic diseases such as coronary heart disease, both doctors and patients should pay attention to the possibility of reflux pharyngitis, and should consult with gastroenterology for gastroscopy to clarify the diagnosis and treat accordingly. At present, the main therapeutic drug is the use of proton pump inhibitors such as esomeprazole or omeprazole or even gastric motility drugs to inhibit gastric acid, promote gastric emptying, and control reflux. 6-8 weeks of continuous medication is recommended, and some suspected cases even without obvious reflux symptoms can be treated on a trial basis. In addition, it is also very important to pay attention to the correction of poor lifestyle, such as quit smoking and alcohol, do not consume all kinds of stimulating food and drinks, eat less dinner, do not eat 2 hours before bedtime, elevate the head of the bed or high pillow and shoulder pad, etc. It is believed that after active treatment and psychological guidance will obtain satisfactory results.