Local anesthesia refers to the application of local anesthetics to the body to temporarily block the sensory nerve conduction in a certain part of the body. Local anesthetics commonly used in clinical practice can be divided into two categories according to their chemical structures: first, esters; second, amides. Commonly used ester local anesthetics are procaine, chloroprocaine, bupivacaine, etc.; amide-type local anesthetics are lidocaine, lidocaine carbonate, bupivacaine, levobupivacaine, ropivacaine, etc.. Local anesthetics vary in their time of action permeability, and are commonly used in clinical practice for surface anesthesia are bupivacaine and procaine. Lidocaine, bupivacaine, levobupivacaine, and ropivacaine, are commonly used in intralesional anesthesia and nerve block anesthesia.