Whether nephrotic syndrome in children can be completely cured cannot be generalized. Some children with nephrotic syndrome caused by primary and secondary factors may be cured by oral glucocorticoid, but some of them are prone to relapse after cure and need to go to the hospital for rechecking regularly. Children with nephrotic syndrome caused by genetic factors generally have poor prognosis and cannot be cured completely.
1. Primary: The most important pathological changes of nephrotic syndrome in children are microscopic lesion type. Microscopic lesion nephropathy is usually sensitive to glucocorticoids and may be cured, but is prone to relapse.
2. Secondary: including allergic purpura nephritis, systemic lupus erythematosus nephritis, etc. Treatment includes hormones and/or immunosuppressants. Hormones include methylprednisolone, prednisone, etc.; immunosuppressants include cyclophosphamide, tacrolimus, cyclosporine, etc. Some patients with secondary nephrotic syndrome are also prone to relapse after cure.
3. Hereditary: Most of the children with nephrotic syndrome cannot be completely cured due to gene mutation. Those diagnosed with hereditary nephrotic syndrome should be followed up regularly, and those who have progressed to uremia stage should receive renal replacement therapy in time.
If children have nephrotic syndrome, parents should bring their children to regular hospitals for timely treatment under the guidance of professional doctors to avoid delay.