Only one ankle pain is not always gout, but also can be seen in other conditions, such as long-term cold, sprain, long standing, osteoarthritis and so on. The main clinical symptoms of acute gout attack are redness, swelling, heat, pain and activity disorder of the joints, and laboratory tests may find that the patient’s uric acid is elevated. If one ankle pain, suspected gout, need to check the uric acid to clarify the cause. In addition, one ankle pain can also be caused by other factors, such as ankle cold for a long time, can also lead to ankle pain; if the ankle joint repeated sprains, can cause traumatic arthritis of the ankle joint, which can lead to pain; can also be caused by osteoarthritis or rheumatism, rheumatoid arthritis and other diseases. Therefore, only one ankle pain is not necessarily gout, and needs to be identified with other conditions. If the diagnosis of gout attack, the patient should try to avoid heavy walking, elevate the affected foot to promote venous return, reduce the symptoms of swelling and pain, can take non-steroidal anti-inflammatory drugs analgesic, and pay attention to the low purine diet, quit smoking and drinking, drinking water, to promote the excretion of uric acid.