The pain in the palm of the foot below the big toe is not necessarily gout, but may also be other diseases, the details are as follows: 1, the first metatarsophalangeal osteoarthritis: the first metatarsophalangeal joints are prone to degenerative changes in the case of prolonged overloading, the patient will have obvious pain in the palm of the foot below the big toe, accompanied by swelling and limited activities. X-ray film will find that the first metatarsophalangeal joints appear serious osteophytes, joint space narrowing, and even joint asymmetry; 2, gouty arthritis: easy to be deposited in the big toe joints, causing symptoms of pain in the toe joints palms, accompanied by localized redness and swelling and limited activities, and the serum uric acid will be significantly elevated; 3, traumatic injuries: localized sprains can also cause pain in the palms of the feet underneath the big toes, accompanied by localized activity limitations and swelling. Trauma: Localized sprains can also cause pain in the ball of the foot below the big toe with local limitation of movement and swelling. The patient usually has a clear history of trauma, and the pain symptoms can be significantly relieved by cold compresses, braking and rest.