Issues related to the follow-up of patients with gastrointestinal mesenchymal tumors

       1.What is a follow-up visit?  To put it plainly, it is the regular review of the patient after the diagnosis of the disease. In professional terms, it means that the patient, the patient’s family and the doctor will keep in touch with each other regularly and review the patient’s health condition according to the doctor’s appointment. Based on the results of the patient’s recovery and review, the doctor will further propose the next stage of recovery review plan or treatment advice.  2.What is the importance of follow-up for patients with gastrointestinal mesenchymal tumor?  For other malignant tumors, the treatment options for recurrence after surgery are limited, mostly chemotherapy and less effective. However, in case of recurrence after surgery or progression of the disease while taking Imatinib, there are several treatment strategies available, and the final outcome depends on the early detection of the disease changes. Therefore, I hope that all gastrointestinal mesenchymal tumor patients must listen carefully to the doctor’s advice for a planned follow-up.  3. Scientific follow-up frequency.  Given that recurrence of gastrointestinal mesenchymal tumor after surgery is mostly between 6 months and 4 years after surgery, the median recurrence time (which can be interpreted as the average recurrence time) is 22 months; and some patients will develop drug resistance 1-2 years after taking imatinib effectively for advanced gastrointestinal mesenchymal tumor, so follow-up is quite important in the first 3 years after treatment.  It is recommended to review every 3 months for 3 years and every 6 months thereafter; every 6 months for patients with low risk of recurrence; and every 2 months for preoperative treatment patients (patients who wish to control their disease by drugs before surgery) until surgery.  4. Routine follow-up contents.  Routine blood, liver and kidney function (the frequency of the above two can be higher), and most importantly, whole abdomen CT enhancement scan. Of course patients with concerns about radiation dose may opt for MRI. During the follow-up period, describe to the doctor whether there are any significant toxic side effects, commonly including body or facial edema, weakness, rash, poor appetite, diarrhea, etc.