There are many reasons for children’s dwarfism, and in order to treat it, we must find out the cause and make a correct diagnosis, and then consider how to treat it. In order to find out the cause of the disease, we should firstly ask the medical history and physical and laboratory examination, and based on the detailed information and laboratory results, we should analyze and judge the cause of children’s dwarfism and finally determine the treatment plan.
1.Bone age film: For children with short stature, first of all, we need to take X-ray pictures (bone age film) of the left wrist and metacarpal fingers to understand the bone age, determine the growth of the child’s bones, the degree of epiphyseal closure (if the epiphysis is closed, there is no possibility of treatment) and growth potential. It is important to know how much height can be grown without treatment in order to know whether treatment is needed or to determine a more reasonable treatment plan.
2, liver and kidney function, blood sugar, thyroid hormone, growth hormone stimulation test, blood routine, etc.: those who need to consider growth hormone treatment, but also do liver and kidney function, blood sugar, blood routine and thyroid hormone, growth hormone stimulation test to understand the growth level, [growth hormone is peak secretion, without stimulation test, it is impossible to know whether growth hormone is normal, the standard growth hormone stimulation test need to do the stimulation test of two drugs separately The standardized growth hormone excitation test needs to be done separately for two drugs, a total of 8~9 time points (using indwelling needles and not repeatedly lancing) and insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein (IGFBP-3).
3. Chromosomes and MRI: Chromosomes are also checked in undeveloped girls to rule out “congenital ovarian hypoplasia (Turner’s syndrome)”, and chromosomes may be checked in a very small number of boys. A magnetic resonance imaging (MRI) or CT of the pituitary gland is usually required to rule out factors such as pituitary tumors that are not suitable for growth hormone application.
Other special tests for dwarfism should be recommended by the attending physician.