TI-RADS4A refers to the enlargement of thyroid nodules in the human body to reach grade IV or grade 4, the degree of enlargement of thyroid nodules in the human body has been graded as grade 1 to grade 5, the risk of enlargement of thyroid nodules is gradually increasing, grade IV individuals should be seriously alerted to the risk of the transformation of thyroid nodules into malignant tumors, they should go to the hospital in time to carry out a puncture of the thyroid gland for pathologic examination, to prevent cancerous transformation of thyroid cells in the human body or mutation. Once the body of the thyroid gland enlargement to grade V is likely to be a malignant tumor of the thyroid gland, grade 3 and below the thyroid gland enlargement belongs to benign or inflammation of the thyroid gland, although all will cause the thyroid gland enlargement, but it does not mean that all the thyroid cells will be cancerous. If the organism develops thyroid disease, it should go to the hospital for treatment in time and take relevant medicines to avoid the deterioration of the condition.