Autoimmune liver, i.e. autoimmune hepatitis, does not have an optimal clinical treatment. Autoimmune hepatitis is a chronic inflammatory disease with predominantly liver damage mediated by an autoimmune response, which is currently incurable and has a certain genetic predisposition. The goal of treatment for autoimmune hepatitis is to control the progression of the disease and avoid the development of cirrhosis and liver failure. Clinical treatment of autoimmune hepatitis is mainly through the use of drugs to inhibit the inflammatory and immune responses, such as the use of glucocorticoids such as prednisone and methylprednisolone to inhibit the inflammatory response, and the use of immunosuppressants such as azathioprine and tacrolimus to inhibit immune responses. For patients whose condition has progressed to end-stage liver disease and acute liver failure, liver transplantation can also be chosen for treatment. In daily life, patients with autoimmune hepatitis should pay attention to observe whether symptoms such as fatigue and abdominal discomfort occur. Patients should undergo regular review to achieve better control of the disease.